RT Book, Section A1 Leeman, Robert F. A1 Sofuoglu, Mehmet A2 Ebert, Michael H. A2 Leckman, James F. A2 Petrakis, Ismene L. SR Print(0) ID 1158265023 T1 Stimulant Use Disorders T2 Current Diagnosis & Treatment: Psychiatry, 3e YR 2019 FD 2019 PB McGraw-Hill Education PP New York, NY SN 9780071754422 LK accessmedicine.mhmedical.com/content.aspx?aid=1158265023 RD 2024/11/07 AB Cocaine and amphetamines are stimulant drugs that activate the central nervous system (CNS), with resulting strong rewarding effects (e.g., euphoria, "rush" and "high") that contribute to high abuse liability. Most clinical characteristics pertain to all stimulant drugs, with certain exceptions such as the long duration of action of methamphetamine compared to the brief action of cocaine. Given this commonality, unless otherwise noted, all discussion in this chapter pertains to stimulant drugs as a whole. Specific comments will be focused primarily on cocaine, followed by methamphetamine, given that these drugs have received the most research attention. Brief specific mention will be made of other stimulants that are commonly abused, such as methylenedioxmethamphetamine (MDMA, commonly known as "ecstasy").