RT Book, Section A1 Katzung, Bertram G. A1 Kruidering-Hall, Marieke A1 Trevor, Anthony J. SR Print(0) ID 1156531044 T1 Clinical Pharmacology of the Antihelminthic Drugs T2 Katzung & Trevor's Pharmacology: Examination & Board Review, 12e YR 2019 FD 2019 PB McGraw-Hill Education PP New York, NY SN 9781259641022 LK accessmedicine.mhmedical.com/content.aspx?aid=1156531044 RD 2024/03/29 AB Antihelminthic drugs have diverse chemical structures, mechanisms of action, and properties. Many act against specific parasites, and few are devoid of significant toxicity to host cells. In addition to the direct toxicity of the drugs, reactions to dead and dying parasites may cause serious toxicity in patients. In the text that follows, the drugs are divided into 3 groups on the basis of the type of helminth primarily affected (nematodes, trematodes, and cestodes). The drugs of choice and alternative agents for selected important helminthic infections are listed in Table 53–1.