RT Book, Section A1 Katzung, Bertram G. A1 Kruidering-Hall, Marieke A1 Trevor, Anthony J. SR Print(0) ID 1156529517 T1 Drugs Used in Coagulation Disorders T2 Katzung & Trevor's Pharmacology: Examination & Board Review, 12e YR 2019 FD 2019 PB McGraw-Hill Education PP New York, NY SN 9781259641022 LK accessmedicine.mhmedical.com/content.aspx?aid=1156529517 RD 2024/03/19 AB The drugs used in clotting and bleeding disorders fall into 2 major groups: (1) drugs used to decrease clotting or dissolve clots already present in patients at risk for vascular occlusion and (2) drugs used to increase clotting in patients with clotting deficiencies. The first group, the anticlotting drugs, includes some of the most commonly used drugs in the United States. Anticlotting drugs are used in the treatment and prevention of myocardial infarction and other acute coronary syndromes, ischemic stroke in patients with atrial fibrillation, and deep vein thrombosis (DVT). Within the anticlotting group, the anticoagulant and thrombolytic drugs are effective in treatment of both venous and arterial thrombosis, whereas antiplatelet drugs are useful only for treatment of arterial disease.