RT Book, Section
A1 Messing, Robert O.
A1 Nestler, Eric J.
A1 State, Matthew W.
A2 Jameson, J. Larry
A2 Fauci, Anthony S.
A2 Kasper, Dennis L.
A2 Hauser, Stephen L.
A2 Longo, Dan L.
A2 Loscalzo, Joseph
SR Print(0)
ID 1156510266
T1 Biology of Psychiatric Disorders
T2 Harrison's Principles of Internal Medicine, 20e
YR 2018
FD 2018
PB McGraw-Hill Education
PP New York, NY
SN 9781259644016
LK accessmedicine.mhmedical.com/content.aspx?aid=1156510266
RD 2024/04/19
AB Psychiatric  disorders  are  central  nervous  system  diseases  characterized  by  disturbances  in  emotion,  cognition,  motivation,  and  socialization.  They  are  highly  heritable,  with  genetic  risk  comprising  20–90%  of  disease  vulnerability.  As  a  result  of  their  prevalence,  early  onset,  and  persistence,  they  contribute  substantially  to  the  burden  of  illness  worldwide.  All  psychiatric  disorders  are  broad  heterogeneous  syndromes  that  currently  lack  well-defined  neuropathology  and  bona  fide  biologic  markers.  Therefore,  diagnoses  continue  to  be  made  solely  from  clinical  observations  using  criteria  in  the  Diagnostic  and  Statistical  Manual  of  Mental  Disorders,  Fifth  Edition  (DSM-5),  of  the  American  Psychiatric  Association.