RT Book, Section
A1 Bleijenberg, Gijs
A1 van der Meer, Jos W. M.
A2 Jameson, J. Larry
A2 Fauci, Anthony S.
A2 Kasper, Dennis L.
A2 Hauser, Stephen L.
A2 Longo, Dan L.
A2 Loscalzo, Joseph
SR Print(0)
ID 1156510229
T1 Chronic Fatigue Syndrome
T2 Harrison's Principles of Internal Medicine, 20e
YR 2018
FD 2018
PB McGraw-Hill Education
PP New York, NY
SN 9781259644016
LK accessmedicine.mhmedical.com/content.aspx?aid=1156510229
RD 2021/04/19
AB Chronic  fatigue  syndrome  (CFS)  is  a  disorder  characterized  by  persistent  and  unexplained  fatigue  resulting  in  severe  impairment  in  daily  functioning.  Besides  intense  fatigue,  most  patients  with  CFS  report  concomitant  symptoms  such  as  pain,  cognitive  dysfunction,  and  unrefreshing  sleep.  Additional  symptoms  can  include  headache,  sore  throat,  tender  lymph  nodes,  muscle  aches,  joint  aches,  post-exertional  malaise,  feverishness,  difficulty  sleeping,  psychiatric  problems,  allergies,  and  abdominal  cramps.  Criteria  for  the  diagnosis  of  CFS  have  been  developed  by  the  U.S.  Centers  for  Disease  Control  and  Prevention  (Table  442-1).  The  Institute  of  Medicine  (IOM;  now  the  National  Academy  of  Medicine)  has  recently  changed  the  diagnostic  criteria  and  proposed  the  name  systemic  exercise  intolerance  disease  (SEID).  To  date,  however,  no  studies  have  been  reported  to  demonstrate  the  usefulness  of  this  change.