RT Book, Section
A1 Brewer, George J.
A2 Jameson, J. Larry
A2 Fauci, Anthony S.
A2 Kasper, Dennis L.
A2 Hauser, Stephen L.
A2 Longo, Dan L.
A2 Loscalzo, Joseph
SR Print(0)
ID 1156564106
T1 Wilson’s Disease
T2 Harrison's Principles of Internal Medicine, 20e
YR 2018
FD 2018
PB McGraw-Hill Education
PP New York, NY
SN 9781259644016
LK accessmedicine.mhmedical.com/content.aspx?aid=1156564106
RD 2024/04/18
AB Wilson’s  disease  is  an  autosomal  recessive  disorder  caused  by  mutations  in  the  ATP7B  gene,  which  encodes  a  membrane-bound,  copper-transporting  ATPase.  Clinical  manifestations  are  caused  by  copper  toxicity  and  primarily  involve  the  liver  and  the  brain.  Because  effective  treatment  is  available,  it  is  important  to  make  this  diagnosis  early.