RT Book, Section A1 Dunaif, Andrea A2 Jameson, J. Larry A2 Fauci, Anthony S. A2 Kasper, Dennis L. A2 Hauser, Stephen L. A2 Longo, Dan L. A2 Loscalzo, Joseph SR Print(0) ID 1155955712 T1 Women’s Health T2 Harrison's Principles of Internal Medicine, 20e YR 2018 FD 2018 PB McGraw-Hill Education PP New York, NY SN 9781259644016 LK accessmedicine.mhmedical.com/content.aspx?aid=1155955712 RD 2024/04/20 AB The clinical discipline of women’s health is well established. Indeed, its emphasis on greater attention to patient education and medical decision-making is a paradigm for what has become known as patient-centered health care. Moreover, the recognition of sex differences in disease processes and health outcomes is an important example of precision medicine. Sex difference refers to the biologic differences conferred by sex chromosomes and hormones. In contrast, gender differences are related to psychosocial roles and cultural expectations. The study of sex differences continues to grow as a scientific discipline. In 2016, the National Institutes of Health recognized its importance by implementing the expectation that sex should be considered as a biologic variable in study designs, analyses, and reporting in not only human but also vertebrate animal research. Strong scientific justification must be provided to limit research to only one sex.