RT Book, Section
A1 Arlt, Wiebke
A2 Jameson, J. Larry
A2 Fauci, Anthony S.
A2 Kasper, Dennis L.
A2 Hauser, Stephen L.
A2 Longo, Dan L.
A2 Loscalzo, Joseph
SR Print(0)
ID 1165971959
T1 Disorders of the Adrenal Cortex
T2 Harrison's Principles of Internal Medicine, 20e
YR 2018
FD 2018
PB McGraw-Hill Education
PP New York, NY
SN 9781259644016
LK accessmedicine.mhmedical.com/content.aspx?aid=1165971959
RD 2024/04/19
AB The  adrenal  cortex  produces  three  classes  of  corticosteroid  hormones:  glucocorticoids  (e.g.,  cortisol),  mineralocorticoids  (e.g.,  aldosterone),  and  adrenal  androgen  precursors  (e.g.,  dehydroepiandrosterone  [DHEA])  (Fig.  379-1).  Glucocorticoids  and  mineralocorticoids  act  through  specific  nuclear  receptors,  regulating  aspects  of  the  physiologic  stress  response  as  well  as  blood  pressure  and  electrolyte  homeostasis.  Adrenal  androgen  precursors  are  converted  in  the  gonads  and  peripheral  target  cells  to  sex  steroids  that  act  via  nuclear  androgen  and  estrogen  receptors.