RT Book, Section
A1 Shah, Ankoor
A1 St. Clair, E. William
A2 Jameson, J. Larry
A2 Fauci, Anthony S.
A2 Kasper, Dennis L.
A2 Hauser, Stephen L.
A2 Longo, Dan L.
A2 Loscalzo, Joseph
SR Print(0)
ID 1157285895
T1 Rheumatoid Arthritis
T2 Harrison's Principles of Internal Medicine, 20e
YR 2018
FD 2018
PB McGraw-Hill Education
PP New York, NY
SN 9781259644016
LK accessmedicine.mhmedical.com/content.aspx?aid=1157285895
RD 2024/04/25
AB Rheumatoid  arthritis  (RA)  is  a  chronic  inflammatory  disease  of  unknown  etiology  characterized  by  a  symmetric  polyarthritis,  the  most  common  form  of  chronic  inflammatory  arthritis.  Since  persistently  active  RA  often  results  in  articular  cartilage  and  bone  destruction  and  functional  disability,  it  is  vital  to  diagnose  and  treat  this  disease  early  and  aggressively  before  damage  ensues.  RA,  a  systemic  disease,  may  also  lead  to  a  variety  of  extraarticular  manifestations,  including  fatigue,  subcutaneous  nodules,  lung  involvement,  pericarditis,  peripheral  neuropathy,  vasculitis,  and  hematologic  abnormalities,  which  must  be  managed  accordingly.