RT Book, Section
A1 John, Roy M.
A1 Stevenson, William G.
A2 Jameson, J. Larry
A2 Fauci, Anthony S.
A2 Kasper, Dennis L.
A2 Hauser, Stephen L.
A2 Longo, Dan L.
A2 Loscalzo, Joseph
SR Print(0)
ID 1156562517
T1 Polymorphic Ventricular Tachycardia and Ventricular Fibrillation
T2 Harrison's Principles of Internal Medicine, 20e
YR 2018
FD 2018
PB McGraw-Hill Education
PP New York, NY
SN 9781259644016
LK accessmedicine.mhmedical.com/content.aspx?aid=1156562517
RD 2024/04/19
AB Sustained  polymorphic  VT  can  be  seen  with  any  form  of  structural  heart  disease.  However,  unlike  sustained  monomorphic  VT,  polymorphic  VT  does  not  always  indicate  a  structural  abnormality  or  focus  of  automaticity.  Reentry  with  continually  changing  reentrant  paths,  spiral  wave  reentry  and  multiple  automatic  foci  are  potential  mechanisms  (Chap.  A9).  Sustained  polymorphic  VT  usually  degenerates  into  ventricular  fibrillation  (VF).  Polymorphic  VT  is  typically  seen  in  association  with  acute  myocardial  infarction  or  ischemia  (MI),  ventricular  hypertrophy,  and  a  number  of  genetic  mutations  that  affect  cardiac  ion  channels  (see  Table  249-1).