RT Book, Section
A1 Hoppe, Jordana E.
A1 Snyder, Robert
A1 Accurso, Frank J.
A1 Siparsky, Georgette
A2 Hay, Jr., William W.
A2 Levin, Myron J.
A2 Deterding, Robin R.
A2 Abzug, Mark J.
SR Print(0)
ID 1153318608
T1 Chemistry & Hematology Reference Intervals
T2 Current Diagnosis & Treatment: Pediatrics, 24e
YR 2018
FD 2018
PB McGraw-Hill Education
PP New York, NY
SN 9781259862908
LK accessmedicine.mhmedical.com/content.aspx?aid=1153318608
RD 2022/05/24
AB Laboratory  tests  provide  valuable  information  necessary  to  evaluate  a  patient’s  condition  and  to  monitor  recommended  treatment.  Chemistry  and  hematology  test  results  are  compared  with  those  of  healthy  individuals  or  those  undergoing  similar  therapeutic  treatment  to  determine  clinical  status  and  progress.  In  the  past,  the  term  normal  ranges  relayed  some  ambiguity  because  statistically,  the  term  normal  also  implied  a  specific  (Gaussian  or  normal)  distribution  and  epidemiologically  it  implied  the  state  of  the  majority,  which  is  not  necessarily  the  desirable  or  targeted  population.  This  is  most  apparent  in  cholesterol  levels,  where  values  greater  than  200  mg/dL  are  common,  but  not  desirable.  Use  of  the  term  reference  range  or  reference  interval  is  therefore  recommended  by  the  International  Federation  of  Clinical  Chemistry  (IFCC)  and  the  Clinical  and  Laboratory  Standards  Institute  (CLSI)  to  indicate  that  the  values  relate  to  a  reference  population  and  clinical  condition.