RT Book, Section
A1 Spragg, David D.
A1 Tomaselli, Gordon F.
A2 Jameson, J. Larry
A2 Fauci, Anthony S.
A2 Kasper, Dennis L.
A2 Hauser, Stephen L.
A2 Longo, Dan L.
A2 Loscalzo, Joseph
SR Print(0)
ID 1155973485
T1 The Bradyarrhythmias: Disorders of the Atrioventricular Node
T2 Harrison's Principles of Internal Medicine, 20e
YR 2018
FD 2018
PB McGraw-Hill Education
PP New York, NY
SN 9781259644016
LK accessmedicine.mhmedical.com/content.aspx?aid=1155973485
RD 2024/10/05
AB Impulses  generated  in  the  sinoatrial  (SA)  node  or  in  ectopic  atrial  loci  are  conducted  to  the  ventricles  through  the  electrically  and  anatomically  complex  atrioventricular  (AV)  node.  As  described  in  Chap.  239,  the  electrophysiologic  properties  of  nodal  tissue  are  distinct  from  atrial  and  ventricular  myocardium.  Cells  located  in  the  AV  node  sit  at  a  relatively  higher  resting  membrane  potential  than  surrounding  atrial  and  ventricular  myocytes,  exhibit  spontaneous  depolarization  during  phase  4  of  the  action  potential,  and  have  slower  phase  0  depolarization  (mediated  by  calcium  influx  in  nodal  tissue)  than  that  seen  in  ventricular  tissue  (mediated  by  sodium  influx).