RT Book, Section
A1 Kennelly, Peter J.
A1 Murray, Robert K.
A1 Jacob, Molly
A1 Varghese, Joe
A2 Rodwell, Victor W.
A2 Bender, David A.
A2 Botham, Kathleen M.
A2 Kennelly, Peter J.
A2 Weil, P. Anthony
SR Print(0)
ID 1160193405
T1 Plasma Proteins & Immunoglobulins
T2 Harper's Illustrated Biochemistry, 31e
YR 2018
FD 2018
PB McGraw-Hill Education
PP New York, NY
SN 9781259837937
LK accessmedicine.mhmedical.com/content.aspx?aid=1160193405
RD 2024/04/23
AB OBJECTIVESAfter  studying  this  chapter,  you  should  be  able  to:List  the  major  functions  of  blood.Describe  the  principal  functions  of  serum  albumin.Explain  how  haptoglobin  protects  the  kidney  against  formation  of  damaging  iron  precipitates.Describe  the  roles  of  ferritin,  transferrin,  and  ceruloplasmin  in  iron  homeostasis.Describe  the  mechanism  by  which  transferrin,  transferrin  receptors,  and  HFE  protein  regulate  the  synthesis  of  hepcidin.Explain  how  iron  homeostasis  can  be  perturbed  by  dietary  deficiencies  or  certain  disorders.Describe  the  general  structures  and  functions  of  the  five  classes  of  immunoglobulins.Explain  how  up  to  a  million  different  immunoglobulins  can  be  generated  utilizing  fewer  than  150  human  genes.Describe  the  activation  and  mode  of  action  of  the  complement  system.Compare  and  contrast  the  adaptive  and  innate  immune  systems.Define  the  term  lectin.Outline  the  key  differences  between  polyclonal  and  monoclonal  antibodies.Describe  the  salient  features  of  autoimmune  and  immunodeficiency  disorders.