RT Book, Section
A1 Bender, David A.
A1 Mayes, Peter A.
A2 Rodwell, Victor W.
A2 Bender, David A.
A2 Botham, Kathleen M.
A2 Kennelly, Peter J.
A2 Weil, P. Anthony
SR Print(0)
ID 1160192080
T1 The Citric Acid Cycle: The Central Pathway of Carbohydrate, Lipid, & Amino Acid Metabolism
T2 Harper's Illustrated Biochemistry, 31e
YR 2018
FD 2018
PB McGraw-Hill Education
PP New York, NY
SN 9781259837937
LK accessmedicine.mhmedical.com/content.aspx?aid=1160192080
RD 2024/04/18
AB OBJECTIVESAfter  studying  this  chapter,  you  should  be  able  to:Describe  the  reactions  of  the  citric  acid  cycle  and  the  reactions  that  lead  to  the  production  of  reducing  equivalents  that  are  oxidized  in  the  mitochondrial  electron  transport  chain  to  yield  ATP.Explain  the  importance  of  vitamins  in  the  citric  acid  cycle.Explain  how  the  citric  acid  cycle  provides  both  a  route  for  catabolism  of  amino  acids  and  also  a  route  for  their  synthesis.Describe  the  main  anaplerotic  pathways  that  permit  replenishment  of  citric  acid  cycle  intermediates,  and  how  the  withdrawal  of  oxaloacetate  for  gluconeogenesis  is  controlled.Describe  the  role  of  the  citric  acid  cycle  in  fatty  acid  synthesis.Explain  how  the  activity  of  the  citric  acid  cycle  is  controlled  by  the  availability  of  oxidized  cofactors.Explain  how  hyperammonemia  can  lead  to  loss  of  consciousness.