RT Book, Section
A1 Weil, P. Anthony
A2 Rodwell, Victor W.
A2 Bender, David A.
A2 Botham, Kathleen M.
A2 Kennelly, Peter J.
A2 Weil, P. Anthony
SR Print(0)
ID 1160191528
T1 Membranes: Structure & Function
T2 Harper's Illustrated Biochemistry, 31e
YR 2018
FD 2018
PB McGraw-Hill Education
PP New York, NY
SN 9781259837937
LK accessmedicine.mhmedical.com/content.aspx?aid=1160191528
RD 2024/04/23
AB OBJECTIVESAfter  studying  this  chapter,  you  should  be  able  to:Know  that  biologic  membranes  are  mainly  composed  of  a  lipid  bilayer  and  associated  proteins  and  glycoproteins.  The  major  lipids  are  phospholipids,  cholesterol,  and  glycosphingolipids.Appreciate  that  membranes  are  asymmetric,  dynamic  structures  containing  a  mixture  of  integral  and  peripheral  proteins.Describe  the  widely  accepted  fluid  mosaic  model  of  membrane  structure.Understand  the  concepts  of  passive  diffusion,  facilitated  diffusion,  active  transport,  endocytosis,  and  exocytosis.Recognize  that  transporters,  ion  channels,  the  Na+  −  K+-ATPase,  receptors,  and  gap  junctions  are  important  participants  in  membrane  function.Be  aware  that  a  variety  of  disorders  result  from  abnormalities  of  membrane  structure  and  function,  including  familial  hypercholesterolemia,  cystic  fibrosis,  hereditary  spherocytosis,  among  others.