RT Book, Section
A1 Kennelly, Peter J.
A1 Rodwell, Victor W.
A2 Rodwell, Victor W.
A2 Bender, David A.
A2 Botham, Kathleen M.
A2 Kennelly, Peter J.
A2 Weil, P. Anthony
SR Print(0)
ID 1160188621
T1 Amino Acids & Peptides
T2 Harper's Illustrated Biochemistry, 31e
YR 2018
FD 2018
PB McGraw-Hill Education
PP New York, NY
SN 9781259837937
LK accessmedicine.mhmedical.com/content.aspx?aid=1160188621
RD 2024/04/18
AB OBJECTIVESAfter  studying  this  chapter,  you  should  be  able  to:Diagram  the  structures  and  write  the  three-  and  one-letter  designations  for  each  of  the  amino  acids  present  in  proteins.Provide  examples  of  how  each  type  of  R  group  of  the  protein  amino  acids  contributes  to  their  chemical  properties.List  additional  important  functions  of  amino  acids  and  explain  how  certain  amino  acids  in  plant  seeds  can  severely  impact  human  health.Name  the  ionizable  groups  of  the  protein  amino  acids  and  list  their  approximate  pKa  values  as  free  amino  acids  in  aqueous  solution.Calculate  the  pH  of  an  unbuffered  aqueous  solution  of  a  polyfunctional  amino  acid  and  the  change  in  pH  that  occurs  following  the  addition  of  a  given  quantity  of  strong  acid  or  alkali.Define  pI  and  explain  its  relationship  to  the  net  charge  on  a  polyfunctional  electrolyte.Explain  how  pH,  pKa  and  pI  can  be  used  to  predict  the  mobility  of  a  polyelectrolyte,  such  as  an  amino  acid,  in  a  direct-current  electrical  field.Describe  the  directionality,  nomenclature,  and  primary  structure  of  peptides.Describe  the  conformational  consequences  of  the  partial  double-bond  character  of  the  peptide  bond  and  identify  the  bonds  in  the  peptide  backbone  that  are  free  to  rotate.