RT Book, Section A1 Janson, Lee W. A1 Tischler, Marc E. SR Print(0) ID 1152118320 T1 DNA/RNA FUNCTION AND PROTEIN SYNTHESIS T2 The Big Picture: Medical Biochemistry YR 2018 FD 2018 PB McGraw-Hill Education PP New York, NY SN 9780071637916 LK accessmedicine.mhmedical.com/content.aspx?aid=1152118320 RD 2024/03/28 AB The nucleus is often represented as a relatively empty structure, containing only deoxyribonucleic acid (DNA) being replicated and transcribed along with a few accessory molecules to help in the process. To the contrary, the nucleus is actually a highly organized, membrane-bound structure that is literally filled with proteins, nucleotides, carbohydrates, and lipids with multiple functions. Various proteins are involved, along with the nuclear membrane, in the organization of chromosomes, which also helps to regulate the processes of DNA replication and transcription, and, subsequently, protein synthesis. Other proteins directly influence the expression of genes via direct interactions with specific nucleotide sequences. Post-translational modifications affect both protein function and direct particular proteins to intracellular and/or extracellular destinations.