RT Book, Section
A1 Balogun, Seki A.
A1 Turgut, Faruk H.
A1 Abdel-Rahman, Emaad
A2 Lerma, Edgar V.
A2 Rosner, Mitchell H.
A2 Perazella, Mark A.
SR Print(0)
ID 1149117148
T1 Aging and the Kidney
T2 CURRENT Diagnosis & Treatment: Nephrology & Hypertension, 2e
YR 2017
FD 2017
PB McGraw-Hill Education
PP New York, NY
SN 9781259861055
LK accessmedicine.mhmedical.com/content.aspx?aid=1149117148
RD 2024/04/24
AB Aging  is  an  inevitable  biological  process  that  affects  many  organ  systems,  of  which  the  kidney  is  one  of  the  most  significantly  affected.  The  process  of  aging  is  associated  with  renal  changes,  both  physiologic  and  anatomical  that  differentiates  the  aged  kidney  from  a  younger  one.  These  changes  increase  suspectibility  to  kidney  injury  and  may  lead  to  decline  in  kidney  function.  Apart  from  age  associated  changes  in  the  kidney,  older  adults  are  more  likely  to  have  associated  chronic  medical  conditions  such  as  hypertension,  diabetes  mellitus  (DM),  issues  with  polypharmacy  and  exposure  to  other  nephrotoxins.  These  conditions  may  further  predispose  older  adults  to  chronic  kidney  disease  (CKD)  and  in  some  cases  ultimately  lead  to  end-stage  kidney  disease  (ESKD).