RT Book, Section A1 Balogun, Seki A. A1 Turgut, Faruk H. A1 Abdel-Rahman, Emaad A2 Lerma, Edgar V. A2 Rosner, Mitchell H. A2 Perazella, Mark A. SR Print(0) ID 1149117148 T1 Aging and the Kidney T2 CURRENT Diagnosis & Treatment: Nephrology & Hypertension, 2e YR 2017 FD 2017 PB McGraw-Hill Education PP New York, NY SN 9781259861055 LK accessmedicine.mhmedical.com/content.aspx?aid=1149117148 RD 2024/10/12 AB Aging is an inevitable biological process that affects many organ systems, of which the kidney is one of the most significantly affected. The process of aging is associated with renal changes, both physiologic and anatomical that differentiates the aged kidney from a younger one. These changes increase suspectibility to kidney injury and may lead to decline in kidney function. Apart from age associated changes in the kidney, older adults are more likely to have associated chronic medical conditions such as hypertension, diabetes mellitus (DM), issues with polypharmacy and exposure to other nephrotoxins. These conditions may further predispose older adults to chronic kidney disease (CKD) and in some cases ultimately lead to end-stage kidney disease (ESKD).