RT Book, Section
A1 Mathur, Piyush
A1 Mehta, Ravindra L.
A2 Lerma, Edgar V.
A2 Rosner, Mitchell H.
A2 Perazella, Mark A.
SR Print(0)
ID 1149116535
T1 Continuous Renal Replacement Therapy
T2 CURRENT Diagnosis & Treatment: Nephrology & Hypertension, 2e
YR 2017
FD 2017
PB McGraw-Hill Education
PP New York, NY
SN 9781259861055
LK accessmedicine.mhmedical.com/content.aspx?aid=1149116535
RD 2023/01/26
AB Renal  replacement  therapy  (RRT)  can  be  provided  as  hemodialysis,  hemofiltration,  or  a  combination  thereof  and  as  intermittent,  or  as  continuous  therapy.  Continuous  renal  replacement  therapy  (CRRT)  represents  a  number  of  technically  distinct  modalities  characterized  by  slow  per-minute  solute  clearance  and  ultrafiltration  rates  that  are  spread  over  most  or  all  of  the  day  to  minimize  wide  metabolic  or  volume  shifts.  The  longer  duration  of  therapy  has  been  associated  with  greater  hemodynamic  stability  and  a  higher  likelihood  of  kidney  recovery  compared  to  standard  intermittent  hemodialysis  (IHD).  CRRT  encompass  several  methods  of  hemofiltration  and  hemodialysis  and  is  being  increasingly  utilized  for  managing  patients  with  AKI  in  the  intensive  care  unit  (ICU)  setting.  This  chapter  reviews  the  major  terms  used  in  the  delivery  of  CRRT,  the  most  prominent  clinical  and  technical  issues  encountered  by  the  healthcare  teams,  and  promising  technologies  that  may  improve  the  efficacy  and  future  applicability  of  the  relevant  modalities.