RT Book, Section A1 Reilly, Robert F. A2 Lerma, Edgar V. A2 Rosner, Mitchell H. A2 Perazella, Mark A. SR Print(0) ID 1149112077 T1 Disorders of Phosphorus Balance: Hyperphosphatemia and Hypophosphatemia T2 CURRENT Diagnosis & Treatment: Nephrology & Hypertension, 2e YR 2017 FD 2017 PB McGraw-Hill Education PP New York, NY SN 9781259861055 LK accessmedicine.mhmedical.com/content.aspx?aid=1149112077 RD 2024/10/04 AB Approximately 80–85% of phosphorus in the body is contained in bone, 14% in cells and soft tissues, and 1% in the extracellular fluid. A very small fraction of the intracellular pool is inorganic and available for synthesis of high-energy phosphorus-containing molecules. Neutral phosphate balance is maintained with dietary intakes over a wide range from 800 to 1500 mg/day. Phosphorus homeostasis is dependent upon the interaction of three organ systems: the gastrointestinal (GI) tract, bone, and kidney. A general overview of phosphorus metabolism is shown in Figure 7–1.