RT Book, Section
A1 Rogers, Joseph G.
A1 Patel, Chetan B.
A1 Milano, Carmelo A.
A2 Fuster, Valentin
A2 Harrington, Robert A.
A2 Narula, Jagat
A2 Eapen, Zubin J.
SR Print(0)
ID 1161717025
T1 MECHANICALLY ASSISTED CIRCULATION
T2 Hurst's The Heart, 14e
YR 2017
FD 2017
PB McGraw-Hill Education
PP New York, NY
SN 9780071843249
LK accessmedicine.mhmedical.com/content.aspx?aid=1161717025
RD 2024/04/20
AB Advanced  heart  failure  is  characterized  by  the  clinical  signs  and  symptoms  of  congestion,  low  cardiac  output,  and  progressive  organ  dysfunction  with  an  annualized  mortality  of  80%  to  90%  despite  optimal  medical  and  electrical  therapies.1  Cardiac  transplantation  remains  the  gold  standard  treatment  for  stage  D  heart  failure,  but  the  worldwide  donor  shortage  has  resulted  in  highly  selective  criteria  and  long  waiting  times  for  a  suitable  organ.  The  option  of  mechanically  assisted  circulation  as  a  viable  treatment  alternative  for  this  population  has  gained  gradual  acceptance  over  the  past  decade.  The  original  mechanical  blood  pumps  were  designed  to  replicate  the  human  heart,  resulting  in  large,  pulsatile  devices  with  a  normal  adult  stroke  volume.  The  conceptual  model  of  assisted  circulation  has  evolved  to  smaller,  less  complex  continuous  flow  pumps.  The  Interagency  Registry  for  Mechanically  Assisted  Circulation  (INTERMACS)  has  documented  the  growth  of  the  field  with  detailed  clinical  information  on  >  15,000  individual  patients  treated  with  mechanical  circulatory  support  (MCS)  in  the  United  States.2