RT Book, Section
A1 Holford, Nicholas H. G.
A2 Katzung, Bertram G.
SR Print(0)
ID 1148432924
T1 Pharmacokinetics & Pharmacodynamics: Rational Dosing & the Time Course of Drug Action
T2 Basic & Clinical Pharmacology, 14e
YR 2017
FD 2017
PB McGraw-Hill Education
PP New York, NY
SN 9781259641152
LK accessmedicine.mhmedical.com/content.aspx?aid=1148432924
RD 2024/04/24
AB CASE  STUDYAn  85-year-old,  60-kg  woman  with  a  serum  creatinine  of  1.8  mg/dL  has  atrial  fibrillation.  A  decision  has  been  made  to  use  digoxin  to  control  the  rapid  heart  rate.  The  target  concentration  of  digoxin  for  the  treatment  of  atrial  fibrillation  is  1  ng/mL.  Tablets  of  digoxin  are  available  that  contain  62.5  micrograms  (mcg)  and  250  mcg.  What  maintenance  dose  would  you  recommend?