RT Book, Section
A1 Schaefer, G. Bradley
A1 Thompson, Jr., James N.
SR Print(0)
ID 1147722129
T1 The Organization of Development
T2 Medical Genetics: An Integrated Approach
YR 2017
FD 2017
PB McGraw-Hill Education
PP New York, NY
SN 9780071664387
LK accessmedicine.mhmedical.com/content.aspx?aid=1147722129
RD 2024/04/25
AB A  conclusion  one  could  draw  from  the  first  two  chapters  is  that  the  role  of  genes  in  determining  phenotypes  is  complex  and  dynamic.  That  is  true.  It  is  an  important  insight  that  should  be  kept  in  mind  when  evaluating  a  genetic  question.  But,  by  the  same  token,  complexity  does  not  necessarily  mean  that  rules  and  order  are  weak.  In  this  chapter  we  will  explore  some  of  these  rules,  specifically  the  question  of  how  gene  regulation  activates  a  particular  gene  in  the  appropriate  developmental  context  and  how  molecular  signals  carry  out  large-scale  patterning  to  organize  the  structure  of  the  body  in  early  development.