RT Book, Section A1 Eschenhagen, Thomas A2 Brunton, Laurence L. A2 Hilal-Dandan, Randa A2 Knollmann, Björn C. SR Print(0) ID 1162538083 T1 Treatment of Ischemic Heart Disease T2 Goodman & Gilman's: The Pharmacological Basis of Therapeutics, 13e YR 2017 FD 2017 PB McGraw-Hill Education PP New York, NY SN 9781259584732 LK accessmedicine.mhmedical.com/content.aspx?aid=1162538083 RD 2024/03/28 AB AbbreviationsACE: angiotensin-converting enzymeACEI: angiotensin-converting enzyme inhibitorACS: acute coronary syndromeALDH2: mitochondrial aldehyde dehydrogenaseARB: angiotensin receptor blockerAV: atrioventricularCABG: coronary artery bypass graftingCAD: coronary artery diseaseCOX-1: cyclooxygenase isoform 1CYP: cytochrome P450EC50: half-maximal effective concentrationEMA: European Medicines AgencyeNOS: endothelial NOSFDA: U.S. Food and Drug AdministrationFFA: free fatty acidGI: gastrointestinalGTN: glyceryl trinitrate (nitroglycerin)HCM: hypertrophic cardiomyopathyHCN: hyperpolarization-activated cyclic nucleotide–gatedHMG-CoA: 3-hydroxy-3-methylglutaryl coenzyme AiNOS: inducible NOSIP3: inositol 1,4,5-trisphosphateISDN: isosorbide dinitrateISMN: isosorbide-5-mononitrateMI: myocardial infarctionnNOS: neuronal NOSNO: nitric oxideNOS: nitric oxide synthaseNSTEMI: non–ST-elevation myocardial infarctionPDE: cyclic nucleotide phosphodiesterasePgp: P-glycoproteinPLC: phospholipase CrTPA: recombinant tissue plasminogen activatorSA: sinoatrialSNS: sympathetic nervous systemSTEMI: ST-segment elevation myocardial infarctionTn: troponinTxA2: thromboxane A2