RT Book, Section A1 Waxman, Stephen G. SR Print(0) ID 1137638591 T1 The Reticular Formation T2 Clinical Neuroanatomy, 28e YR 2017 FD 2017 PB McGraw-Hill Education PP New York, NY SN 9780071847704 LK accessmedicine.mhmedical.com/content.aspx?aid=1137638591 RD 2024/04/19 AB The reticular formation plays a central role in the regulation of the state of consciousness and arousal. It consists of a complex network of interconnected circuits of neurons in the tegmentum of the brain stem, the lateral hypothalamic area, and the medial, intralaminar, and reticular nuclei of the thalamus (Fig 18–1). Many of these neurons are serotonergic (using serotonin as their neurotransmitter), or noradrenergic. Axons from these nonspecific thalamic nuclei project to most of the cerebral cortex, where they modulate the level of activity of large numbers of neurons.