RT Book, Section
A1 Via, Michael A.
A1 Mechanick, Jeffrey I.
A2 Oropello, John M.
A2 Pastores, Stephen M.
A2 Kvetan, Vladimir
SR Print(0)
ID 1136415787
T1 Endocrine Dysfunction Leading to Critical Illness
T2 Critical Care
YR 1
FD 1
PB McGraw-Hill Education
PP New York, NY
SN 9780071820813
LK accessmedicine.mhmedical.com/content.aspx?aid=1136415787
RD 2024/10/08
AB KEY  POINTSThe  immune-neuroendocrine  response  of  critical  illness  (CI)  is  marked  by  hypercatabolism  and  diminished  hypothalamic-pituitary-end-organ  function.Despite  low  circulating  growth  hormone  (GH)  levels  in  CI,  the  administration  of  exogenous  GH  is  detrimental.Central  adrenal  insufficiency  typically  results  from  overly  rapid  tapering  of  corticosteroid  dosing  or  increased  stress  in  a  patient  who  was  recently  tapered  off  of  corticosteroids.CI  or  relative  adrenal  insufficiency,  though  real  and  relevant,  is  still  the  subject  of  great  interest  among  intensivists  and  changes  in  definitions  and  management  are  likely  to  change  in  the  near  future.Diabetic  ketoacidosis  typically  occurs  in  patients  with  type  1  diabetes  that  are  newly  diagnosed,  acutely  ill,  or  resulting  from  missed  scheduled  insulin  doses.