RT Book, Section A1 Smith, Dustin T. A1 Adhyaru, Bhavin A2 McKean, Sylvia C. A2 Ross, John J. A2 Dressler, Daniel D. A2 Scheurer, Danielle B. SR Print(0) ID 1137605515 T1 Summary Literature: Practice Guidelines and Systematic Reviews T2 Principles and Practice of Hospital Medicine, 2e YR 2017 FD 2017 PB McGraw-Hill Education PP New York, NY SN 9780071843133 LK accessmedicine.mhmedical.com/content.aspx?aid=1137605515 RD 2022/08/13 AB Summary literature represents the highest quality of evidence and the top portion of the evidence-based medicine pyramid. In this chapter, summary literature refers specifically to practice guidelines and systematic reviews. If done properly, authors will have performed a comprehensive systematic review of the literature available as well as summarized findings from the available literature for both of these types of manuscripts. For practice guidelines, the summary typically exists in the form of graded recommendations. For systematic reviews, the summary comes in the form of a meta-analysis where a quantitative statistical analysis is conducted of pooled data from several separate but similar studies. Although articles featuring literature reviews (ie, narrative review, aka “review articles”) by authors exist for many clinical topics in medicine, the methods used for reviewing the literature in these articles are not necessarily systematic or comprehensive and it is typically left to the authors’ discretion for which data and studies to include. Table 10-1 offers a comparison of narrative reviews, systematic reviews, meta-analysis, and guidelines.