RT Book, Section A1 Kasper, Dennis L. A1 Fauci, Anthony S. A1 Hauser, Stephen L. A1 Longo, Dan L. A1 Jameson, J. Larry A1 Loscalzo, Joseph SR Print(0) ID 1128785332 T1 Fungal Infections T2 Harrison's Manual of Medicine, 19e YR 2016 FD 2016 PB McGraw-Hill Education PP New York, NY SN 9780071828529 LK accessmedicine.mhmedical.com/content.aspx?aid=1128785332 RD 2024/03/29 AB Yeasts (e.g., Candida, Cryptococcus) appear microscopically as round, budding forms; molds (e.g., Aspergillus, Rhizopus) appear as filamentous forms called hyphae; and dimorphic fungi (e.g., Histoplasma) are spherical in tissue but appear as molds in the environment. – Endemic fungi (e.g., Coccidioides) are not part of the normal human microbiota and infect hosts preferentially by inhalation.– Opportunistic fungi (e.g., Candida and Aspergillus) invade the host from normal sites of colonization (e.g., mucous membranes or the GI tract).Definitive diagnosis of any fungal infection requires histopathologic identification of the fungus invading tissue and accompanying evidence of an inflammatory response.