RT Book, Section A1 Kasper, Dennis L. A1 Fauci, Anthony S. A1 Hauser, Stephen L. A1 Longo, Dan L. A1 Jameson, J. Larry A1 Loscalzo, Joseph SR Print(0) ID 1128781762 T1 Principles of Critical Care Medicine T2 Harrison's Manual of Medicine, 19e YR 2016 FD 2016 PB McGraw-Hill Education PP New York, NY SN 9780071828529 LK accessmedicine.mhmedical.com/content.aspx?aid=1128781762 RD 2024/10/09 AB Initial care of critically ill pts must often be performed rapidly and before a thorough medical history has been obtained. Physiologic stabilization begins with the principles of advanced cardiovascular life support and frequently involves invasive techniques such as mechanical ventilation and renal replacement therapy to support organ systems that are failing. A variety of severity-of-illness scoring systems, such as APACHE (acute physiology and chronic health evaluation), have been developed. Although these tools are useful for ensuring similarity among groups of pts involved in clinical trials, guiding resource allocation, or monitoring quality assurance, their relevance to individual pts is less clear. These scoring systems are not typically used to guide clinical management.