RT Book, Section A1 Mehta, Rohtesh S. A1 Oran, Betul A1 Shpall, Elizabeth J. A2 Kantarjian, Hagop M. A2 Wolff, Robert A. SR Print(0) ID 1126741283 T1 Alternative Donor Transplants: Cord Blood Transplant T2 The MD Anderson Manual of Medical Oncology, 3e YR 2016 FD 2016 PB McGraw-Hill Medical PP New York, NY SN 9780071847940 LK accessmedicine.mhmedical.com/content.aspx?aid=1126741283 RD 2024/03/28 AB The numbers of allogeneic stem cell transplants (SCTs) performed in the United States have increased steadily, from about 7,500 in 1994-1995 to over 13,500 in 2010-2011, in patients above the age of 20 years (1). Donor identification has been a constant challenge, and only 30% of patients who need allogeneic SCT have a matched sibling donor. The National Marrow Donor Program (NMDP) and its cooperative international registries have about 16 million volunteer donors. It is estimated that 75% of white patients, but only 16% of African Americans and other minority patients, will be able to find a suitably matched unrelated donor (MUD) and proceed to transplantation (2). Mismatched related (often haploidentical), cord blood (CB) or mismatched unrelated donors (MMUDs) with either peripheral blood (PB) or bone marrow (BM) graft sources are potential options for patients in need of a SCT but lacking a matched related donor (MRD) or unrelated donor.