RT Book, Section A1 Hoffman, Barbara L. A1 Schorge, John O. A1 Bradshaw, Karen D. A1 Halvorson, Lisa M. A1 Schaffer, Joseph I. A1 Corton, Marlene M. SR Print(0) ID 1125289814 T1 Preinvasive Lesions of the Lower Genital Tract T2 Williams Gynecology, 3e YR 2016 FD 2016 PB McGraw-Hill Education PP New York, NY SN 978-0-07-184908-1 LK accessmedicine.mhmedical.com/content.aspx?aid=1125289814 RD 2024/03/29 AB Office gynecology frequently involves the diagnosis and management of preinvasive lower genital tract disease, most often involving the uterine cervix. Since widespread introduction of the Papanicolaou (Pap) test in the 1950s, cervical cancer screening has reduced the incidence of and mortality rate from invasive cervical cancer by more than 70 percent (Howlader, 2014). This is true despite a continued rise in the incidence of preinvasive lesions (Kurdgelashvili, 2013). Approximately 7 percent of U.S. women who undergo Pap testing will have an abnormal result (Wright, 2012). An abnormal screening test prompts further patient evaluation, usually with colposcopy and biopsy. Histologic results are more definitive and inform appropriate management.