RT Book, Section
A1 MA, Lichtman
A1 MS, Shafer
A1 RE, Felgar
A1 N, Wang
SR Print(0)
ID 1138038815
T1 Acute Myelogenous Leukemia
T2 Lichtman's Atlas of Hematology 2016
YR 2017
FD 2017
PB McGraw-Hill Education
PP New York, NY
SN 9780071602679
LK accessmedicine.mhmedical.com/content.aspx?aid=1138038815
RD 2024/04/25
AB Graphic  Jump  LocationView  Full  Size||Download  Slide  (.ppt)IX.B.001Acute  myelogenous  leukemia  with  minimal  maturation.  Flow  cytometry.  Staining  pattern  of  marrow  cells.  The  upper  left  panel  shows  the  pattern  of  leukocyte  common  antigen  (CD45)  versus  side-scatter.  The  leukemic  blast  population  has  dimmer  CD45  staining  than  lymphocytes  (the  very  bright  population  in  the  upper  left  of  the  graph),  but  with  low  side-scatter  (right  angle  light  scatter).  This  population  accounts  for  95%  of  all  events.  The  remaining  panels  demonstrate  some  of  the  characteristic  markers  in  myeloblasts  (CD34  marks  immature  precursor  cells;  HLA-DR  is  a  class  II  major  histocompatibility  antigen  that  is  usually  lost  by  the  promyelocyte  stage  of  maturation;  CD13,  CD33,  and  CD117  are  markers  characteristic  of  immature  myeloid  lineage).