RT Book, Section A1 MA, Lichtman A1 MS, Shafer A1 RE, Felgar A1 N, Wang SR Print(0) ID 1138037225 T1 Eosinophils T2 Lichtman's Atlas of Hematology 2016 YR 2017 FD 2017 PB McGraw-Hill Education PP New York, NY SN 9780071602679 LK accessmedicine.mhmedical.com/content.aspx?aid=1138037225 RD 2024/04/18 AB Graphic Jump LocationView Full Size||Download Slide (.ppt)II.D.001Eosinophils, normal. Buffy coat (white cell concentrate). The field contains two eosinophils, two neutrophils, and a lymphocyte. The eosinophils are typical cells; bilobed nucleus, present in virtually all normal eosinophils, and a cytoplasm filled with eosinophilic granules. The granules do not obscure the nucleus as is characteristic in basophils. Some small areas without granules (degranulation) are present. Note that the neutrophil granules are too small to be resolved by the light microscope, whereas the large eosinophilic granules can be resolved. This is especially evident if eosinophilic granules are released from disrupted cells and are free in the surrounding area.