RT Book, Section A1 Hollander, Judd E. A1 Diercks, Deborah B. A2 Tintinalli, Judith E. A2 Stapczynski, J. Stephan A2 Ma, O. John A2 Yealy, Donald M. A2 Meckler, Garth D. A2 Cline, David M. SR Print(0) ID 1142184416 T1 Acute Coronary Syndromes T2 Tintinalli’s Emergency Medicine: A Comprehensive Study Guide, 8e YR 2016 FD 2016 PB McGraw-Hill Education PP New York, NY SN 9780071794763 LK accessmedicine.mhmedical.com/content.aspx?aid=1142184416 RD 2024/04/19 AB Ischemic heart disease is the leading cause of death among adults in the United States, with more than 405,000 people dying annually. Atherosclerotic disease of the epicardial coronary arteries—termed coronary artery disease (CAD)—accounts for the vast majority of patients with ischemic heart disease. The predominant symptom of CAD is chest pain, and patient concern over potential acute heart disease contributes to the >8 million visits each year to U.S. EDs. In a typical adult ED population with acute chest pain, about 15% of patients will have an acute coronary syndrome (ACS). ACS encompasses unstable angina through acute myocardial infarction (AMI). Of patients with an ACS, approximately one third have an AMI, and the remainder have unstable angina.