RT Book, Section A1 Garris, Shauna A1 Hughes, Caitlin A2 Tintinalli, Judith E. A2 Stapczynski, J. Stephan A2 Ma, O. John A2 Yealy, Donald M. A2 Meckler, Garth D. A2 Cline, David M. SR Print(0) ID 1121518993 T1 Acute Agitation T2 Tintinalli’s Emergency Medicine: A Comprehensive Study Guide, 8e YR 2016 FD 2016 PB McGraw-Hill Education PP New York, NY SN 9780071794763 LK accessmedicine.mhmedical.com/content.aspx?aid=1121518993 RD 2024/04/23 AB EDs are the portal of access to the healthcare system for most patients with acute agitation and acute behavioral or mental health disorders.1 Agitation is one of the most common manifestations of mental health and behavioral disorders, dementia, and intoxication and withdrawal syndromes. The last consensus updates for acute agitation were published in 2006,2 prior to the release of newer therapeutic agents and prior to the recognition of QTc prolongation with acutely administered psychotropics. This review provides a general pharmacotherapeutic approach for acute agitation and acute behavioral emergencies.