RT Book, Section
A1 LoVecchio, Frank
A1 Mattison, Erik
A2 Tintinalli, Judith E.
A2 Stapczynski, J. Stephan
A2 Ma, O. John
A2 Yealy, Donald M.
A2 Meckler, Garth D.
A2 Cline, David M.
SR Print(0)
ID 1121499359
T1 Atypical and Serotonergic Antidepressants
T2 Tintinalli’s Emergency Medicine: A Comprehensive Study Guide, 8e
YR 2016
FD 2016
PB McGraw-Hill Education
PP New York, NY
SN 9780071794763
LK accessmedicine.mhmedical.com/content.aspx?aid=1121499359
RD 2024/04/19
AB Atypical  and  serotonergic  antidepressants  are  commonly  referred  to  as  newer  or  second-generation  antidepressants,  to  distinguish  them  from  the  first-generation  monoamine  oxidase  inhibitors  and  cyclic  antidepressants.  As  a  group,  these  antidepressants  are  the  most  popular  form  of  psychopharmacologic  therapy  for  the  treatment  of  major  depression,  obsessive-compulsive  disorder,  panic  disorders,  and  eating  disorders.1  These  antidepressants  produce  less  severe  toxicity  in  overdose  and  are  associated  with  fewer  fatalities  than  either  cyclic  antidepressants  or  monoamine  oxidase  inhibitors.2,3  This  favorable  overdose  profile  is  tempered  by  the  U.S.  Food  and  Drug  Administration  black  box  warning  regarding  the  use  of  some  agents  by  patients  <24  years  old  due  to  increased  suicidal  ideation  and  behavior.