RT Book, Section
A1 Williams-Johnson, Jean
A1 Williams, Eric
A2 Tintinalli, Judith E.
A2 Stapczynski, J. Stephan
A2 Ma, O. John
A2 Yealy, Donald M.
A2 Meckler, Garth D.
A2 Cline, David M.
SR Print(0)
ID 1121494428
T1 Sickle Cell Disease and Hereditary Hemolytic Anemias
T2 Tintinalli’s Emergency Medicine: A Comprehensive Study Guide, 8e
YR 2016
FD 2016
PB McGraw-Hill Education
PP New York, NY
SN 9780071794763
LK accessmedicine.mhmedical.com/content.aspx?aid=1121494428
RD 2024/04/20
AB Hereditary  anemias  result  from  defects  in  hemoglobin  production,  abnormalities  in  red  blood  cell  (RBC)  metabolism,  or  changes  within  RBC  membrane  structure.  Increased  hemolysis  occurs  because  the  RBCs  produced  are  either  abnormal  or  sustain  damage  after  release  from  the  bone  marrow,  and  are  removed  from  the  circulation,  primarily  by  the  spleen.  Depending  on  the  compensatory  rate  of  production,  the  concentration  of  circulating  erythrocytes  may  decrease,  resulting  in  anemia.