RT Book, Section A1 Qamar, Amir A. A2 Greenberger, Norton J. A2 Blumberg, Richard S. A2 Burakoff, Robert SR Print(0) ID 1119991430 T1 Liver Transplantation T2 CURRENT Diagnosis & Treatment: Gastroenterology, Hepatology, & Endoscopy, 3e YR 2016 FD 2016 PB McGraw-Hill Education PP New York, NY SN 9780071837729 LK accessmedicine.mhmedical.com/content.aspx?aid=1119991430 RD 2024/04/24 AB ESSENTIAL CONCEPTSHepatitis C and hepatocellular carcinoma are among the leading indications for liver transplantation in the United States.Thorough medical, psychiatric, and social evaluation is required prior to listing patients for transplantation.The Model for End-Stage Liver Disease (MELD) score is widely used for prioritizing patients on the transplant waiting list.Liver biopsy is needed to confirm the diagnosis of acute rejection, which is common and occurs in up to 60% of patients.Surgical complications generally occur within days to weeks and medical complications months or years later.Biliary strictures and leaks occur in 15% of patients after transplantation.Long-term immunosuppression, with calcineurin inhibitors, is associated with an increased risk of renal failure.