RT Book, Section
A1 Rutherford, Anna
A1 Dienstag, Jules L.
A2 Greenberger, Norton J.
A2 Blumberg, Richard S.
A2 Burakoff, Robert
SR Print(0)
ID 1119990255
T1 Viral Hepatitis
T2 CURRENT Diagnosis & Treatment: Gastroenterology, Hepatology, & Endoscopy, 3e
YR 2016
FD 2016
PB McGraw-Hill Education
PP New York, NY
SN 9780071837729
LK accessmedicine.mhmedical.com/content.aspx?aid=1119990255
RD 2024/04/25
AB ESSENTIALS  OF  DIAGNOSISHepatitis  A–E  cause  most  recognized  cases  of  acute  viral  hepatitis;  hepatitis  B,  C,  and  D  cause  most  recognized  cases  of  chronic  viral  hepatitis.Hepatitis  A  and  E,  which  are  transmitted  by  the  fecal-oral  route,  are  self-limited  and  do  not  cause  chronic  infection,  except  that  chronic  infection  with  hepatitis  E  has  been  described  in  immunocompromised  hosts.Hepatitis  B,  C,  and  D  are  acquired  percutaneously;  all  can  result  in  chronic  infection.Hepatitis  D  can  occur  only  in  a  host  already  or  simultaneously  infected  with  hepatitis  B  virus.All  five  forms  can  cause  fulminant  hepatitis,  but  B,  D,  and  E  are  common  causes,  whereas  A  and  C  are  very  rare  causes.Diagnostic  tests  appropriate  to  different  clinical  situations  detect  specific  viral  antigens  and  antibodies  in  serum  by  sensitive  immunoassay  and  viral  DNA/RNA  by  sensitive  amplification  assays  (eg,  polymerase  chain  reaction  [PCR]).