RT Book, Section A1 Kumar, Sonal A1 Qamar, Amir A. A2 Greenberger, Norton J. A2 Blumberg, Richard S. A2 Burakoff, Robert SR Print(0) ID 1119989963 T1 Acute Liver Failure T2 CURRENT Diagnosis & Treatment: Gastroenterology, Hepatology, & Endoscopy, 3e YR 2016 FD 2016 PB McGraw-Hill Education PP New York, NY SN 9780071837729 LK accessmedicine.mhmedical.com/content.aspx?aid=1119989963 RD 2024/04/19 AB ESSENTIALS OF DIAGNOSISDrugs, toxins, viral hepatitis, and hypoperfusion are the most common causes of acute liver failure (ALF).Laboratory findings may confirm the cause and severity of presentation.Consider acetaminophen toxicity in all patients, even without a history of toxic ingestion, particularly when serum aminotransferase levels are very high (>1000 units).Depending on timing of ingestion, acetaminophen levels may not be elevated even in cases of overdose.Rapid diagnostic and psychiatric evaluation is required at presentation.