RT Book, Section
A1 Hamilton, Matthew J.
A1 Castells, Mariana
A1 Greenberger, Norton J.
A2 Greenberger, Norton J.
A2 Blumberg, Richard S.
A2 Burakoff, Robert
SR Print(0)
ID 1119988363
T1 Mast Cell Disorders
T2 CURRENT Diagnosis & Treatment: Gastroenterology, Hepatology, & Endoscopy, 3e
YR 2016
FD 2016
PB McGraw-Hill Education
PP New York, NY
SN 9780071837729
LK accessmedicine.mhmedical.com/content.aspx?aid=1119988363
RD 2024/04/18
AB ESSENTIALS  OF  DIAGNOSIS  FOR  MAST  CELL  ACTIVATION  SYNDROMESigns  and  symptoms  of  mast  cell  activation  that  involve  at  least  two  organ  systems  and  may  include  abdominal  pain,  diarrhea,  flushing,  headache,  and  concentration  difficulties.No  other  medical  disorder  better  explains  these  signs  and  symptoms.Objective  evidence  of  mast  cell  activation  while  symptomatic  including  elevated  levels  of  tryptase  on  a  blood  test,  and/or  elevated  levels  of  mast  cell  metabolites  including  histamine  and/or  prostaglandin  in  a  24-hour  urine  specimen.Reduced  symptoms  with  medications  that  block  mast  cell  mediators  such  as  antihistamines,  cromolyn,  and  leukotriene  antagonists.