RT Book, Section A1 Lim, Ramona A1 Syngal, Sapna A1 Stoffel, Elena M. A2 Greenberger, Norton J. A2 Blumberg, Richard S. A2 Burakoff, Robert SR Print(0) ID 1119988163 T1 Hereditary Gastrointestinal Cancer Syndromes T2 CURRENT Diagnosis & Treatment: Gastroenterology, Hepatology, & Endoscopy, 3e YR 2016 FD 2016 PB McGraw-Hill Education PP New York, NY SN 9780071837729 LK accessmedicine.mhmedical.com/content.aspx?aid=1119988163 RD 2024/04/19 AB ESSENTIALS OF DIAGNOSISApproximately 3–5% of colorectal cancers (CRCs) are caused by inherited gene mutations associated with hereditary nonpolyposis colorectal cancer (HNPCC) (Lynch syndrome) or adenomatous polyposis syndromes.Genetic testing is clinically available for several hereditary gastrointestinal cancer syndromes and can be used to guide cancer screening recommendations.