RT Book, Section
A1 Zhu, Zhenglun
A2 Greenberger, Norton J.
A2 Blumberg, Richard S.
A2 Burakoff, Robert
SR Print(0)
ID 1119986477
T1 Gastrointestinal Manifestations of Immunodeficiency
T2 CURRENT Diagnosis & Treatment: Gastroenterology, Hepatology, & Endoscopy, 3e
YR 2016
FD 2016
PB McGraw-Hill Education
PP New York, NY
SN 9780071837729
LK accessmedicine.mhmedical.com/content.aspx?aid=1119986477
RD 2024/04/19
AB ESSENTIAL  CONCEPTSRecurrent  infections  and  diarrhea  are  the  most  common  gastrointestinal  manifestations  of  immunodeficiency.Some  pathogens  (eg,  Mycobacterium  avium  complex)  are  unique  to  immunocompromised  hosts;  others  (eg,  Cryptosporidium,  Giardia  lamblia)  cause  self-limited  diarrhea  in  healthy  hosts  but  chronic  diarrhea  in  immunosuppressed  patients.In  patients  without  a  specific  diagnosis  after  routine  study,  endoscopic  evaluation  with  biopsy  is  important  in  establishing  the  diagnosis.Candida  species,  herpes  simplex  virus  (HSV),  cytomegalovirus  (CMV),  and  Mycobacterium  species  are  the  most  frequent  causative  agents  of  infectious  esophagitis  in  an  immunocompromised  host.In  immunocompromised  patients,  opportunistic  infections  are  a  major  cause  of  abdominal  pain  and  can  evolve  rapidly.The  frequency  of  intestinal  lymphomas  is  increased  in  patient  with  common  variable  immunodeficiency  (Chua  et  al  2008).