RT Book, Section A1 Kaushansky, Kenneth A1 Kipps, Thomas J. A2 Brunton, Laurence L. A2 Chabner, Bruce A. A2 Knollmann, Björn C. SR Print(0) ID 1127868984 T1 Hematopoietic Agents: Growth Factors, Minerals, and Vitamins T2 Goodman & Gilman's: The Pharmacological Basis of Therapeutics, 12e YR 2015 FD 2015 PB McGraw-Hill Education PP New York, NY SN 9780071624428 LK accessmedicine.mhmedical.com/content.aspx?aid=1127868984 RD 2023/02/01 AB The finite life span of most mature blood cells requires their continuous replacement, a process termed hematopoiesis. New cell production must respond to basal needs and states of increased demand. Red blood cell production can increase >20-fold in response to anemia or hypoxemia, white blood cell production increases dramatically in response to a systemic infection, and platelet production can increase 10- to 20-fold when platelet consumption results in thrombocytopenia.