RT Book, Section
A1 Kaushansky, Kenneth
A1 Kipps, Thomas J.
A2 Brunton, Laurence L.
A2 Chabner, Bruce A.
A2 Knollmann, Björn C.
SR Print(0)
ID 1127868984
T1 Hematopoietic Agents: Growth Factors, Minerals, and Vitamins
T2 Goodman & Gilman's: The Pharmacological Basis of Therapeutics, 12e
YR 2015
FD 2015
PB McGraw-Hill Education
PP New York, NY
SN 9780071624428
LK accessmedicine.mhmedical.com/content.aspx?aid=1127868984
RD 2022/01/24
AB The  finite  life  span  of  most  mature  blood  cells  requires  their  continuous  replacement,  a  process  termed  hematopoiesis.  New  cell  production  must  respond  to  basal  needs  and  states  of  increased  demand.  Red  blood  cell  production  can  increase  >20-fold  in  response  to  anemia  or  hypoxemia,  white  blood  cell  production  increases  dramatically  in  response  to  a  systemic  infection,  and  platelet  production  can  increase  10-  to  20-fold  when  platelet  consumption  results  in  thrombocytopenia.