TY - CHAP M1 - Book, Section TI - Pancreatic Hormones, Antidiabetic Agents, & Glucagon A1 - Trevor, Anthony J. A1 - Katzung, Bertram G. A1 - Kruidering-Hall, Marieke PY - 2015 T2 - Katzung & Trevor's Pharmacology: Examination & Board Review, 11e AB - In the endocrine pancreas, the islets of Langerhans contain at least 4 types of endocrine cells, including A (alpha, glucagon producing), B (beta, insulin, and amylin producing), D (delta, somatostatin producing), and F (pancreatic polypeptide producing). Of these, the B (insulin-producing) cells are the most numerous.The most common pancreatic disease requiring pharmacologic therapy is diabetes mellitus, a deficiency of insulin production or effect. Diabetes is treated with several parenteral formulations of insulin and oral or parenteral noninsulin antidiabetic agents. Glucagon, a hormone that affects the liver, cardiovascular system, and gastrointestinal tract, can be used to treat severe hypoglycemia. SN - PB - McGraw-Hill Education CY - New York, NY Y2 - 2022/05/20 UR - accessmedicine.mhmedical.com/content.aspx?aid=1123462252 ER -