TY - CHAP M1 - Book, Section TI - Pulmonary Arteriovenous Malformations A1 - Goodenberger, Daniel M. A1 - Chakinala, Murali A2 - Grippi, Michael A. A2 - Elias, Jack A. A2 - Fishman, Jay A. A2 - Kotloff, Robert M. A2 - Pack, Allan I. A2 - Senior, Robert M. A2 - Siegel, Mark D. PY - 2015 T2 - Fishman's Pulmonary Diseases and Disorders, 5e AB - Pulmonary arteriovenous malformations (PAVMs) were first described in the late 19th century; Churton1 reported the autopsy findings in a young boy with cyanosis in 1897. Based on the correlation of physical with postmortem findings, the triad of cyanosis, clubbing, and polycythemia was identified with PAVM in 1932.2 Hereditary hemorrhagic telangiectasia (HHT) was first connected to PAVM in 1938.3 As described below (Causes and Disease Associations), HHT is often intimately related to PAVMs—a fact that prompts the following discussion of the history of HHT. SN - PB - McGraw-Hill Education CY - New York, NY Y2 - 2024/04/18 UR - accessmedicine.mhmedical.com/content.aspx?aid=1122362996 ER -