TY - CHAP M1 - Book, Section TI - Therapeutic Hypothermia A1 - Abella, Benjamin S. A1 - Leary, Marion A2 - Hall, Jesse B. A2 - Schmidt, Gregory A. A2 - Kress, John P. PY - 2015 T2 - Principles of Critical Care, 4e AB - Induced hypothermia has been shown to reduce mortality when applied after resuscitation from cardiac arrest.Current guidelines recommend induced hypothermia for out-of-hospital cardiac arrest (OHCA) shockable rhythms and suggest consideration of induced hypothermia for OHCA nonshockable rhythms and in-hospital patients.In unconscious adults after out-of-hospital cardiac arrest, mild hypothermia (36°C) appears to be as effective as more extreme hypothermia (33°C) with regard to survival and neurological function.Induced hypothermia may have benefit for other disease processes such as myocardial infarction and stroke.The mechanisms by which hypothermia acts are multifaceted and a focus of much current investigation. SN - PB - McGraw-Hill Education CY - New York, NY Y2 - 2024/03/28 UR - accessmedicine.mhmedical.com/content.aspx?aid=1107716164 ER -