TY  - CHAP
M1  - Book, Section
TI  - Pulmonary Circulation
A1  - Naeije, R.
A2  - Grippi, Michael A.
A2  - Elias, Jack A.
A2  - Fishman, Jay A.
A2  - Kotloff, Robert M.
A2  - Pack, Allan I.
A2  - Senior, Robert M.
A2  - Siegel, Mark D.
PY  - 2015
T2  - Fishman's Pulmonary Diseases and Disorders, 5e
AB  - The  discovery  of  the  pulmonary  circulation  was  reported  in  the  13th  century  by  Ibn  al-Nafis  (1213–1288)  in  the  “Commentary  on  Anatomy  in  Avicenna's  Canon”  and,  probably  independently,  in  the  16th  century  by  Michael  Servetus  (1511–1553)  in  the  “The  Restoration  of  Christianity.”1  However,  it  has  only  been  recently  realized  that  the  pulmonary  circulation  as  a  separate  high-flow  low-pressure  system  is  the  end  result  of  an  evolutionary  process  aimed  at  the  optimization  of  gas  exchange  of  endothermic  birds  and  mammals.2  Evolution  from  ancestors  of  fishes  to  amphibians,  reptiles,  and  finally  birds  and  mammals  has  led  to  progressively  greater  oxygen  consumption  requiring  thinner  pulmonary  blood–gas  barrier.  The  alveolocapillary  membrane  in  mammals  is  a  vulnerable  structure  only  0.3  μm  thick.  Preservation  of  the  integrity  of  this  barrier  has  been  made  possible  by  the  complete  separation  of  the  pulmonary  circulation  from  the  systemic  circulation.  This  evolution  has  been  accompanied  by  a  progressive  unloading  and  reshaping  of  the  right  ventricle  (RV)  as  a  thin-walled  flow  generator.  
SN  - 
PB  - McGraw-Hill Education
CY  - New York, NY
Y2  - 2024/04/16
UR  - accessmedicine.mhmedical.com/content.aspx?aid=1122355141
ER  -