TY - CHAP M1 - Book, Section TI - Myeloproliferative Disorders and Myelodysplastic Syndromes A1 - Aster, Jon C. A1 - DeAngelo, Daniel J. A2 - Bunn, H. Franklin A2 - Aster, Jon C. PY - 2011 T2 - Pathophysiology of Blood Disorders AB - LEARNING OBJECTIVESAfter studying this chapter you should understand:The pathogenic role of specific tyrosine kinase mutations in various myeloproliferative disorders.The role of BCR-ABL in the diagnosis and targeted therapy of chronic myelogenous leukemia.The diagnostic and pathogenic role of JAK2 mutations in polycythemia vera.The pathophysiology and clinical features of the myelodysplastic syndromes. SN - PB - McGraw-Hill Medical CY - New York, NY Y2 - 2024/03/29 UR - accessmedicine.mhmedical.com/content.aspx?aid=1104131688 ER -