TY  - CHAP
M1  - Book, Section
TI  - Metabolic Syndrome
A1  - Joy, Tisha R.
A1  - Hegele, Robert A.
A2  - Murray, Michael F.
A2  - Babyatsky, Mark W.
A2  - Giovanni, Monica A.
A2  - Alkuraya, Fowzan S.
A2  - Stewart, Douglas R.
PY  - 2014
T2  - Clinical Genomics: Practical Applications in Adult Patient Care
AB  - Disease  summary:Metabolic  syndrome  (MetS)  is  a  complex  genetic  disorder,  involving  the  interaction  of  multiple  genetic  loci  with  environmental  factors.MetS  consists  of  three  of  the  five  following  criteria:  increased  waist  circumference  (Table  12-1);  triglyceride  (TG)  level  greater  than  or  equal  to  150  mg/dL  (1.7  mmol/L)  or  drug  treatment  for  elevated  TG;  high-density  lipoprotein-cholesterol  (HDL-C)  less  than  40  mg/dL  (1  mmol/L)  in  males  or  less  than  50  mg/dL  (1.3  mmol/L)  in  females  or  drug  treatment  for  reduced  HDL-C  level;  systolic  blood  pressure  (SBP)  greater  than  or  equal  to  130  mm  Hg  and/or  diastolic  blood  pressure  (DBP)  greater  than  or  equal  to  85  mm  Hg  or  antihypertensive  drug  treatment  in  a  patient  with  a  history  of  elevated  blood  pressure  (BP);  fasting  glucose  greater  than  or  equal  to  100  mg/dL  (5.6  mmol/L)  or  drug  treatment  for  elevated  glucose.Individuals  with  MetS  have  a  twofold  increased  risk  for  cardiovascular  disease  (CVD)  and  fivefold  increased  risk  for  type  2  diabetes  (DM2)  compared  to  individuals  without  MetS.  
SN  - 
PB  - McGraw-Hill Education
CY  - New York, NY
Y2  - 2024/04/18
UR  - accessmedicine.mhmedical.com/content.aspx?aid=1102698790
ER  -